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News
The first "D-HEST Research Day" more
Swiss Society for Biomaterials Award 2012 more
Taylor and Francis Prize 2012 more
NEW: Colloquium in Biomechanics more
Change from D-MAVT to D-HEST more
50 Years of Biomechanics at ETH Zurich, 17th and 18th, June 2011! more
ETH Medal for Outstanding Doctoral Thesis more
Ptychographic X-ray computed tomography at the nanoscale
Nature. 2010; 467:436-9.
In this letter, a novel X-ray computed tomography technique at the nanoscale is described, which was successfully applied to quantitatively assess the local bone density and to resolve the osteocyte lacuno-canalicular network (see picture) at a resolution below 100 nm.
Hierarchical microimaging of bone structure and function

Nature Rev Rheumatol. 2009 Jul;5(7):373-81.
In this review, strategies for new three-dimensional approaches for functional imaging in the study of micro- and ultrastructural bone are presented. The focus is on hierarchical assessment of bone failure using combined experimental and computational approaches.
Modern biomechanical investigations of the human body include the mechanics of the musculo-skeletal system and movement control from a macroscopic (organs) level down to a microscopic (cells) level, the basic elements of life and growth.
Many diseases like osteoporosis, arthritis, or muscle atrophy lead to reduced strength of the tissues concerned. At risk are the elderly and/or immobilized people due to age, illness, or injury and astronauts in a microgravity environment. To be able to monitor this risk in an early stage of development and to quantify optimal treatment and rehabilitation results is crucial for the welfare of society.
At our Institute we focus on the "musculo-skeletal system of the human body" and we are interested in the material properties of mammalian tissue. To quantify changes and adaptations of these materials through ontogenesis (from birth to death), and the plasticity (adaptation to mechanical demands) of these materials are of prime interest. In contrast to inorganic materials, biological tissue can change its mechanical properties to fulfill the requirements of work, leisure, and even in peak performance sports activities.
The Institute for Biomechanics is a multidisciplinary research unit dedicated to the biomechanical investigation of the human body. It currently consists of three professorships covering different areas of musculo-skeletal biomechanics.
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