Dr. Esther Wehrle

Dr.  Esther Wehrle

Dr. Esther Wehrle

Lecturer at the Department of Health Sciences and Technology

ETH Zürich

Institut für Biomechanik

GLC H 21.1

Gloriastrasse 37/ 39

8092 Zürich

Switzerland

Additional information

Research area

Dr. Dr. Esther Wehrle’s research focuses on musculoskeletal adaptation and regeneration, osteosarcopenia, aging and the potential of mechanical intervention therapies for improving bone properties and musculoskeletal regeneration. Based on her multidisciplinary background (veterinary medicine, biomedical engineering, molecular biology), previous and current projects employ multi-disciplinary approaches (e.g. in vivo models, gene editing, imaging) to improve our understanding of musculoskeletal mechanobiology and regeneration.

Esther Wehrle is a Senior Research Associate and Lecturer at the Institute for Biomechanics at ETH Zurich. She is leading the In vivo mechanomics team within theLaboratory for Bone Biomechanics. The multidisciplinary team (1 Postdoc, 3 PhD students) is aiming for a systems-level understanding of the mechano-molecular mechanisms governing load-induced adaptation and regeneration of the musculoskeletal system.

Membership

Honours

Year Distinction
2017 SGV Travel award for the CRISPR workshop in Berkeley (Swiss Laboratory Animal Science Association)
2016 ETH Postdoc fellowship, cofounded by Marie-Curie Actions
2016 SBMS Travel award for the TERMIS in Uppsala (Swiss Bone & Mineral Society)
2015 ESB Travel award for the ESB in Prague (European Society of Biomechanics)
2014 DadorW Travel grant for the Osteologie in Munich (Deutsche Akademie d. osteologischen & rheumatologischen Wissenschaften)
2014 Finalist in the Young Investigator Symposium (DadorW) at the Osteologie in Munich
2012 UNC Travel grant for the Retreat in Molecular Medicine and Genetics at Myrtle Beach, USA (University of North Carolina at Chapel Hill)

Additional information

Esther Wehrle's background is in veterinary medicine (LMU Munich) and biomedical engineering (TU Munich). After working in a referral clinic for small animalscall_made in the UK, she returned to academia, where she focused on molecular biological methods and bone healing during doctoral projects in Munich (Dr. med. vet.call_made) and Ulm (Dr. rer. nat.call_made). In 2014, she joined the Institute for Biomechanics at ETHZ to work on treatment options for bone regeneration within the Biodesign EU projectcall_made. Subsequently, she obtained an ETH Postdoc fellowship to study the mechano-molecular regulation of fracture healing (2016-2017). Currently, she is continuing the work on bone healing, and she is also managing an ERC projectcall_made dealing with the mechanomics of bone adaptation in aging, aiming to develop new and optimize current intervention therapies for osteoporosis and fracture healing. Further extending the multidisciplinary expertise on bone research to the musculoskeletal system will be the focus of a recently awarded SNF/COST Grantcall_made dealing with “Spatial genomics of musculoskeletal regeneration in a translational mouse model of premature aging” embedded within the Genomics of MusculoSkeletal traits Translational Network (GEMSTONEcall_made).

Course Catalogue

Spring Semester 2024

Number Unit
376-1721-00L Bone Biology and Consequences for Human Health
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